Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash
ConditionDental Diseases
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-45
SponsorCairo University
About this trial
The objective of this study is to compare the effect of Tropolone containing mouthwash versus CHX 0.2% mouthwash in reducing intraoral microorganism. Randomized clinical trial study
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients should be between 18- 45 years of age.
All the volunteers participated in this study will be healthy looking with free medical history.
The volunteers will be asked to suspend their usual oral hygiene practice from two to four days before experiment studying.
Disqualifiers
Patients with a compromised medical condition.
Volunteers that receive any antimicrobial agent during at least two weeks prior to study.
Volunteer with fixed, removable prosthesis or orthodontics appliance.
Volunteers with DMF above six will be excluded.
Trial design
Design model
Parallel
Treatments tested in this trial
Listerine total care zero
Combination productreducing intra-oral cariogenic microorganism.
Chlorhexidine Mouthwash (0.2%).
Combination productChlorhexidine Mouthwash (0.2%).
Treatment groups
30 Participants
are divided into 2 treatment groupsGroup A: Listerine total care zeroExperimental treatment 1 intervention
Group B: Chlorhexidine Mouthwash (0.2%).Active comparator 1 intervention
Trial outcomes
Primary outcomes
1
Bacterial count.
viability counts of Mutans Streptococci lactobacilli
Time frame
Change from the baseline immediate after using mouthwash, at one week after mouthwash and at two weeks after regular use of mouthwashSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov