About this trial
This outpatient study examines how inhaled cannabis, combustible or vaporized, alters lung health and breath biomarkers compared to a tobacco cigarette.
Eligibility criteria
Qualifiers
English-speaking,
Literate adults,
Male or female,
Between the ages of 18 and 55,
Disqualifiers
Physiologic drug dependence on opioids, benzodiazepines, barbiturates, and/or alcohol that would require medical management,
Clinically significant acute medical problem (e.g., infection) or chronic medical problem requiring daily medication or ongoing medical care (e.g., hypertension, cardiovascular disease, diabetes, respiratory disorders [e.g., asthma, COPD]),
Existing or significant lung health problems that could interfere with the study,
Current or history of major psychiatric disorder that would limit the participant's ability to participate in the study (e.g., bipolar disorder),
Trial design
Treatments tested in this trial
- Cannabis (THC)
- Tobacco Cigarette
Treatment groups
Sponsors and collaborators
Hannah Harris
Lead sponsor
University of Kentucky
Sponsor institution