The Effect of Different Intra-canal Medications on Postoperative Pain
ConditionPulp Necrosis, Apical Periodontitis
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-40
SponsorCairo University
About this trial
The aim of this study is to assess the effect of ibuprofen, nitrofurantoin, and calcium hydroxide on postoperative pain after endodontic treatment of necrotic mandibular posterior teeth
Research question/hypothesis:
In patients with necrotic pulps in their mandibular posterior teeth, there would be no difference in the incidence and/or severity of postoperative pain after the use of ibuprofen, nitrofurantoin, or calcium hydroxide intracanal medications.
The study will evaluate postoperative pain after using either of the tested drugs as an intracanal medication amidst visits. of endodontic treatment in cases where pulp necrosis is confirmed.
Eligibility criteria
Qualifiers
Patients with necrotic pulps.
Adult, healthy patients, older than 18 years old
Males and females.
Patient with the ability to understand and use pain scales.
Disqualifiers
Patients' allergies or any other contraindication to any of the medications used.
Pregnant and lactating females.
Patients have been taking pain medication 12 hours earlier.
Patients who have more than one symptomatic mandibular tooth in the same quadrant.
Trial design
Treatments tested in this trial
- ibuprofen
- Nitrofurantoin
- Calcium Hydroxide
Treatment groups
111 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov