The aim of this randomized controlled trial is to find the effects of eccentric and low-load blood flow restriction training on neuromuscular adaptations, muscle strength, functional performance, and disability in patients with knee osteoarthritis
Age group 40-70
Both genders male and female
Clinical diagnosis of knee OA (Kellgren-Lawrence grade 1-3) of the most symptomatic knee.
Pain stable enough to permit exercise on Numeric Pain Rating Scale 3/10.
• Presence of a prosthetic knee in the affected limb.
Inflammatory arthritis (e.g., rheumatoid arthritis) or active flare-up of OA.
Cardiovascular disease contraindicating exercise (e.g., unstable angina, recent MI, uncontrolled hypertension ≥160/100 mmHg).
Pulmonary disease that limits safe participation (e.g., severe COPD, recent exacerbation).