Effect of Aerobic and Resistance Exercise on Quarry Workers
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age30-40
SponsorCairo University
About this trial
The goal of this randomized clinical trial is to compare the effects of aerobic exercise training and resistance exercise training on ventilatory function in quarry workers. It will also evaluate their effects on functional capacity and health-related quality of life (HRQOL).
The main questions it aims to answer are:
Does aerobic exercise training improve ventilatory function more effectively than resistance exercise training? How do aerobic and resistance exercise training affect functional capacity and health-related quality of life in quarry workers?
Researchers will compare aerobic exercise training and resistance exercise training with a control group receiving routine treatment and breathing exercises to determine which intervention is more effective in improving ventilatory function, functional capacity, and health-related quality of life.
Participants will:
Be randomly assigned to one of three groups: an aerobic exercise training group, a resistance exercise training group, or a control group.
Receive the assigned intervention three times per week for eight consecutive weeks.
Undergo ventilatory function assessment using spirometry. Complete assessments of functional capacity and health-related quality of life before and after the intervention.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Male quarry workers.
The age range is between 30 and 40 years.
BMI values from 25 to 29.9 kg/m².
They work 5 to 6 times per weeks with mean exposure range (5-10 years) (Kumar et al., 2014). Exhibited chest manifestations (Respiratory symptoms) like cough, dyspnea, wheeze, and ventilatory impairment with significant reduction in (FEV1/FVC<70% and/or FVC<80% and reduce Peak Expiratory flow 25- 75% (PEF25-75%)(Abdelwahaab et al., 2025).
Disqualifiers
Patients with acute respiratory infections or recent exacerbation(4-6 weeks).
Asthmatic patient.
Chest cancer.
Musculoskeletal diseases and other disorders that could potentially impact the study's findings are excluded from the trial.
Trial design
Design model
Parallel
Treatments tested in this trial
Aerobic exercise training
Procedure/Surgeryparticipants will receive aerobic exercise training in addition to routine medical treatment and breathing exercise training.
Resistance exercise training
Procedure/Surgeryparticipants will receive resistance exercise training in addition to routine medical treatment and breathing exercise training.
Treatment groups
75 Participants
are divided into 3 treatment groupsGroup A: aerobic exercise groupExperimental treatment 1 intervention
Group B: resistance exercise groupExperimental treatment 1 intervention
Group C: control groupNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Forced Expiratory Volume in One Second (FEV1)
Forced Expiratory Volume in One Second (FEV1) will be assessed using spirometry. FEV1 is the volume of air forcefully exhaled during the first second of a forced expiratory maneuver and is expressed in liters (L). Higher values indicate better airway function and ventilatory performance.
Time frame
Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).2
Forced Vital Capacity (FVC)
Forced Vital Capacity (FVC) will be assessed using spirometry. FVC is the maximum volume of air that can be forcefully exhaled after a full inspiration and is expressed in liters (L). Higher values indicate better ventilatory function.
Time frame
Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).3
Forced Expiratory Volume in One Second to Forced Vital Capacity Ratio (FEV1/FVC)
The FEV1/FVC ratio will be assessed using spirometry and expressed as a percentage (%). This parameter reflects the proportion of the forced vital capacity exhaled during the first second of expiration and is commonly used to evaluate airflow limitation. Higher values generally indicate better ventilatory function.
Time frame
Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention).4
Forced Expiratory Flow at 25-75% of Forced Vital Capacity (FEF25-75%)
Forced Expiratory Flow at 25-75% of Forced Vital Capacity (FEF25-75%) will be assessed using spirometry. FEF25-75% represents the average expiratory flow during the middle half of the forced vital capacity maneuver and is expressed in liters per second (L/s). It is considered a sensitive indicator of small airway function. Higher values indicate better small airway function and ventilatory performance.
Time frame
Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention)Secondary outcomes
1
Functional Capacity
Functional capacity will be assessed using the Harvard Step Test. The Brouha Index (BI) will be calculated based on exercise duration and recovery heart rate. Higher scores indicate better functional capacity
Time frame
Baseline (pre-intervention) and at the end of the 8-week intervention period (post-intervention)Sponsors and contacts
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Source ClinicalTrials.gov