The goal of this randomized clinical trial is to learn the effect of using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis in molar teeth. The main question it aims to answer is:
• How effective are using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis? Participants will be asked to fill a visual analogue scale to record their pain, after receiving a root canal treatment while using local corticosteroids or not as well as maintaining apical patency or not.
Researchers will compare the use of corticosteroids and maintaining apical patency in reducing post-operative pain.
Symptomatic acute irreversible pulpitis in molar teeth.
Normal periapical condition including periapical radiography with minimal widening of periodontal ligament.
Normal probing depth.
No medical condition.
Facial or oral paresthesia.
Pregnancy & breastfeeding.
Unrestorable tooth.
Marginal periodontal disease.
Crossover
Non-corticosteroid injection
Procedure/Surgeryno infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Corticosteroid injection
Druginfiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Post-operative pain
Patients were instructed to record their pain level using the Visual Analog Scale
Inflammatory markers
Gingival crevicular fluid samples were collected by periopaper for testing the level of IL-1β and IL-10
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