Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. .

ConditionIntervention
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-55
SponsorCairo University

About this trial

This study aims to assess the effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars with Necrotic Pulps.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Systematically healthy patient (ASA I, II).

Age between 20 and 55 years

Male or female.

Mandibular premolar teeth having single canals diagnosed with pulp necrosis with asymptomatic apical periodontitis.

Disqualifiers

Medically compromised patients having significant systemic disorders. (ASA III or IV).

History of intolerance to NSAIDS.

Immature roots

Vital pulp tissues.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Calcium Hypochlorite as Root Canal Irrigant

    Other intervention

    Calcium Hypochlorite used as root canal irrigant during chemo-mechanical preparation

Treatment groups

30 Participants
are divided into 2 treatment groups
Group A: Calcium Hypochlorite as root canal Irrigant on Postoperative Pain and bacterial load reductionPlacebo comparator 1 intervention
Group B: Sodium Hypochlorite as a root Canal IrrigantActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain in Mandibular Premolars with Necrotic Pulps.

measuring tool: Numerical Rating Scale (NRS). Unite of measurement: Categorical None 0 Mild 1-3 Moderate 4-6 Severe 7-10 Time of measurements: At 6, 12, 24, 48- hours post-treatment.

Time frame
measured at 6, 12, 24, 48 hours after single visit treatment

Secondary outcomes

1

Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Bacterial Reduction in Mandibular Premolars with Necrotic Pulps.

Intracanal bacterial load reduction will be determined by bacterial counting using agar culture technique after root canal preparation (CFUs/ml), The growth will be semi quantitatively determined as very heavy, heavy, moderate, sparse and very sparse depending on the CFU ranging from \>100,000,˂100,000,˂10,000,˂1,000, ˂100 colony forming unit per 1 ml BHI respectively.

Time frame
T0=Baseline immediate after access preparation . T1=Post-instrumentation. T1(within an hour)
2

Number of analgesic tablets taken by the patient after endodontic treatment

Number of analgesic tablets taken by the patient after endodontic treatment Up to 48 hours postoperative. Measuring tool: counting Measurment unite: numerical.

Time frame
Up to 48 hours postoperative.

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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