This study aims to explore whether early intervention for high-risk groups of gestational hyperglycemia can improve insulin resistance and effectively prevent the occurrence of GDM, and evaluate which pathophysiological subtypes of GDM have the best effect on improving maternal and fetal adverse prognosis, so as to provide evidence for stratified management and individualized clinical intervention of high glucose groups in pregnancy
18-55 years old
6-14 weeks of pregnancy
at least one risk factor for GDM
signed a written informed consent
Individuals diagnosed with diabetes or prediabetes prior to pregnancy
currently taking medications affecting blood glucose levels such as metformin
women at risk of miscarriage
individuals with chronic conditions (such as uncontrolled hypertension, severe heart disease)
Parallel
Individual lifestyle management
BehavioralManage the diet, exercise, weight and healthy lifestyle of pregnant women
The incidence of gestational diabetes(GDM)
The 75g 2h oral glucose tolerance test is performed at 24-28 weeks of gestation, and the cut-off points of venous blood glucose values are 5.1mmol/L (fasting), 10.0mmol/L (1h after glucose load), 8.5mmol/L (2h after glucose load). If any one of the three blood glucose measures is above the cut-off points, then GDM is diagnosed..
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This trial is not recruiting at the moment. You can still explore other options:
