Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age13-45
SponsorHacettepe University

About this trial

This prospective observational study will compare recovery after anterior cruciate ligament reconstruction using quadriceps tendon autograft or hamstring tendon autograft. The main goal is to examine differences in knee muscle strength recovery during the early and mid-term postoperative period. Participants aged 13 to 45 years who undergo unilateral ACL reconstruction and meet the eligibility criteria will be followed at Hacettepe University. Knee extensor and flexor strength will be assessed using isometric testing at postoperative weeks 4, 8, and 12 and month 6, and with isokinetic concentric testing at months 3 and 6. Functional outcomes and kinesiophobia will also be evaluated at month 6 using IKDC, KOOS, and the Tampa Scale for Kinesiophobia. All participants will receive the same standard postoperative rehabilitation program under physiotherapist supervision. The study aims to clarify whether graft type is associated with different patterns of muscle strength recovery and functional improvement after ACL reconstruction

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 13 to 45 years

Undergoing anterior cruciate ligament reconstruction with either hamstring tendon autograft or quadriceps tendon autograft

Unilateral anterior cruciate ligament injury

Complete ACL tear with accompanying minimal collateral ligament injury and first-degree meniscal tear

Disqualifiers

Anterior cruciate ligament reconstruction with patellar tendon autograft or allograft

Revision surgery

Systemic or neurological disease

Multiple ligament injuries

Trial population

Participants will be patients with anterior cruciate ligament reconstruction using either quadriceps tendon autograft or hamstring tendon autograft who are referred by an orthopedist to the Hacettepe University Sports Health Unit, meet the eligibility criteria, and provide voluntary consent

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

80 Participants
are grouped into 2 trial groups
Group A: Quadriceps Tendon Autograft
Group B: Hamstring Tendon Autograft

Trial outcomes

Primary outcomes

1

Isometric Quadriceps Muscle Strengt

Maximum voluntary isometric quadriceps strength measured with an IsoMed 2000 dynamometer at 60° of knee flexion. The highest value from 3 maximal 5-second contractions will be recorded and normalized to body weight (Nm/kg).

Time frame
Postoperative weeks 4, 8, and 12, and month 6
2

Isometric Hamstring Muscle Strength

Maximum voluntary isometric hamstring strength measured with an IsoMed 2000 dynamometer at 60° of knee flexion. The highest value from 3 maximal 5-second contractions will be recorded and normalized to body weight (Nm/kg)

Time frame
Postoperative weeks 4, 8, and 12, and month 6

Secondary outcomes

1

Concentric Quadriceps- Hamstring Peak Torque at 60°/s and 180°/s

Concentric quadriceps and hamstring peak torque measured with an IsoMed 2000 dynamometer during isokinetic testing at 60°/s for 5 repetitions and 180°/s for 15 repetitions. Values will be normalized to body weight (Nm/kg).

Time frame
Postoperative months 3 and 6
2

Limb Symmetry Index

Limb Symmetry Index calculated from isokinetic peak torque values as operated limb / contralateral limb × 100.

Time frame
Postoperative months 3 and 6
3

International Knee Documentation Committee Subjective Knee Form Score

Patient-reported knee symptoms, function, and sports activity assessed using the IKDC Subjective Knee Form. Scores range from 0 to 100, with higher scores indicating better knee function.

Time frame
Postoperative month 6
4

Knee Injury and Osteoarthritis Outcome Score

Patient-reported knee outcomes assessed using the KOOS, including pain, symptoms, activities of daily living, sport and recreation, and knee-related quality of life. Scores range from 0 to 100, with higher scores indicating better status.

Time frame
Postoperative month 6

Other outcomes

Sponsors and contacts

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