Effect of Hydrocortisone on Improving Outcome of Pneumatic Reduction of Infantile Intussusception
ConditionIntussusception
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age3-4
SponsorCairo University
About this trial
Intussusception is one of the most frequent causes of acute bowel and second most common cause of acute abdominal pain in pediatric age .95 % of cases are idiopathic, the rest are either due to pathological lead point or post operative. Treatment of intussusception must start with medical resuscitation, then radiological or operative reduction of intussusception.
Our surgery team has used hydrocortisone with the medical resuscitation to improve the success rate of pneumatic reduction and decrease the number of reduction trials.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Infantile Intussusception
Disqualifiers
Peritonitis Pneumoperitoneum Morbid patients
Trial design
Design model
Parallel
Treatments tested in this trial
Hydrocortisone
Drug10 mg/kg with Resuscitation before attempting pneumatic reduction, single dose with Resuscitation before attempting reduction
Saline
Drug100 ml with Resuscitation before attempting pneumatic reduction, single dose with Resuscitation before attempting reduction
Treatment groups
80 Participants
are divided into 2 treatment groupsGroup A: HydrocortisoneExperimental treatment 1 intervention
Group B: SalinePlacebo comparator 1 intervention
Trial outcomes
Primary outcomes
1
Success of Pneumatic Reduction
Comparing number of Successful Pneumatic Reductions in both groups
Time frame
1 HourSecondary outcomes
1
Reducing number of trials of Pneumatic Reduction
Comparing average number of Pneumatic Reduction trials between both groups
Time frame
2 Hours2
Reducing complications
Comparing number of complications in both groups
Time frame
2 HoursSponsors and contacts
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Source ClinicalTrials.gov