About this trial
This research aims to assess the effect of low versus high dialysate sodium concentration during hemodialysis on dialysis recovery time
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients with end-stage renal disease who have been prescribed long term hemodialysis and undergo four-hour HD treatments three times a week for more than 90 days.
Patient must be at least 18 years old. They must be able to read and write, as well as be in complete mental health.
Disqualifiers
Inability to complete the surveys due to reading or hearing difficulties, actual instability of clinical condition that necessitate hospitalization, dementia, active malignancy or liver failure.
Trial design
Parallel
Treatments tested in this trial
high dialysate Na
Other interventionhigh dialysate sodium (Na = 141 mmol/L) for 8 weeks
low dialysate Na
Other interventionlow dialysate sodium (Na = 136 mmol/L) for 8 weeks
Treatment groups
Trial outcomes
Primary outcomes
Change in dialysis recovery time
By assessing the patients' responses to the single open-ended question, "How long does it take you to recover from a dialysis session?"
Secondary outcomes
Change in plasma sodium concentration
measuring plasma sodium concentration
Change in the inter-dialytic weight gain
measuring the inter-dialytic weight gain
Change in blood pressure (systolic, diastolic, mean)
measuring in blood pressure (systolic, diastolic, mean)
Occurrence of intradialytic hypotension
incidence of intradialytic hypotension
Sponsors and contacts
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