About this trial
Tissue repair is an essential process that reestablishes tissue integrity and regular function. Nevertheless, different therapeutic factors and clinical conditions may interfere in this process of periapical healing.The success of root canal treatment is affected by the correct choice of clinical protocol.
These factors are dependent on the sanitization process (instrumentation, irrigating solution, irrigating strategies, and intracanal dressing) the apical limit of the root canal preparation and obturation, and the quality of the sealer. The challenges affecting the healing process of endodontically treated teeth include control of the inflammation of pulp or infectious processes and simultaneous neutralization of unpredictable provocations to the periapical tissue.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients with mature permanent teeth.
Patients with apical periodontitis.
Maxillary anterior teeth only will be involved.
Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
Disqualifiers
Patients with immature canals.
Patients with swelling.
Pregnant females.
Patients who could/would not participate in a 1-year follow-up.
Trial design
Parallel
Treatments tested in this trial
AH plus sealer
Procedure/Surgeryto evaluate and compare postoperative pain and periapical healing after root canal treatment using two different base endodontic sealers: * NeoSEALER Flo * AH plus Resin sealer
Treatment groups
Trial outcomes
Primary outcomes
Treatment of Postoperative Pain
Patients will be evaluated for postoperative pain via (NRS) to record the intensity of pain.as follows: 0 reading represents "no pain" ; 1- 3 reading represents "mild pain" ; 4- 6 reading represents "moderate pain" and 7- 10 reading represents "severe pain".
Secondary outcomes
Periapical Healing
Periapical healing will be evaluated by comparing the size of the initial lesion pre-operatively and postoperatively (after 6 and 12 months), using periapical radiographs and CBCT. This will be aggregated in percentage (%).
Sponsors and contacts
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