Effect of Neuromuscular Electrical Stimulation on Phrenic Nerve Regeneration Post Cardiac Surgeries

ConditionPost-cardiac Surgery

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age25-45

SponsorCairo University

About this trial

This study will be conducted to investigate the effect of neuromuscular electrical stimulation on phrenic regeneration post cardiac surgery

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients post cardiac surgery (coronary artery bypass graft, valve repair or replacement ).

Patients referred by physician.

Medically stable patients.

Both genders

Disqualifiers

Patients with rib fracture.

Patients developing lung cancer.

Patients have dementia.

Patients on mechanical ventilator after 24 hours

Trial design

Design model

Parallel

Treatments tested in this trial

Transcutaneous electrical diaphragmatic stimulation intervention
Device
It will be applied on diaphragm, 30 min per session ,3 days/week for 4 weeks at a stimulation frequency of 30 Hz, pulse width of 400 μs, the intensity was gradually increased until visible muscle contraction was observed.
traditional physiotherapy program
Other intervention
The participants will receive traditional physiotherapy ( postural drainage, percussion , diaphragmatic breathing, phase 1 cardiac Rehabilitation and balance training ) three times per week for 4 weeks

Treatment groups

60 Participants

are divided into 2 treatment groups

Group A: Transcutaneous electrical diaphragmatic stimulation intervention and traditional physiotherapy groupExperimental treatment 2 interventions

Group B: Traditional physiotherapy groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

Phrenic nerve conduction study: motor latency

Nihon Kohden Neuropak M1 MEB-9200 EMG machine, made in Japan will be used to measure phrenic nerve conduction study. Motor latency is the impulse traveled from the stimulation site to the recording site is called latency and it is measured in milliseconds (ms). its normal value: (5.74ms -7.10 ms).

Time frame

4 weeks

Phrenic nerve conduction study: Amplitude

Nihon Kohden Neuropak M1 MEB-9200 EMG machine, made in Japan will be used to measure phrenic nerve conduction study. Amplitude represents the maximal action potential depolarization and voltage gradient for all depolarized fibers of the phrenic nerve. it is measured in microvolt or millivolt (mv). its normal value: (0.47 mv-0.83 mv).

Time frame

4 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: