Effect of Resuscitation on Gastric Emptying Using POCUS in Pediatric Trauma Patients
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age2-7
SponsorAssiut University
About this trial
Pediatric trauma often leads to hemorrhagic shock, which reduces blood flow to the digestive tract and delays gastric emptying. This delay can cause fluid and food to remain in the stomach, increasing the risk of pulmonary aspiration during urgent airway management or emergency anesthesia. Point-of-care ultrasound (POCUS) is a bedside, non-invasive tool that allows clinicians to evaluate stomach contents and estimate gastric volume in real time.
The primary purpose of this study is to evaluate whether restoring systemic blood flow through hemodynamic resuscitation improves gastric emptying and decreases gastric residual volume in injured children.
Participants aged 2 to 7 years presenting to the emergency department with trauma and hemorrhagic shock will receive standard resuscitation according to pediatric advanced life support guidelines. Bedside gastric ultrasound will be performed to measure the antral cross-sectional area and calculate gastric residual volume before resuscitation begins, immediately following initial resuscitation, and every 6 hours for up to 48 hours. Ultrasound procedures are observational and will not delay any standard trauma care or urgent surgical interventions.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Pediatric patients aged 2 to 7 years presenting with trauma.
Presenting with hemorrhagic shock requiring hemodynamic resuscitation (diagnosed according to Advanced Paediatric Life Support [APLS] guidelines based on clinical and laboratory evidence of inadequate tissue perfusion secondary to acute blood loss, such as age-adjusted hypotension, tachycardia, prolonged capillary refill time > 2 seconds, weak peripheral pulses, altered mental status, elevated serum lactate, and/or increased base deficit).
Hemodynamically stable enough to undergo point-of-care gastric ultrasound (POCUS) examination without delaying emergency medical management.
Disqualifiers
Known gastrointestinal diseases affecting gastric motility (e.g., gastric outlet obstruction, intestinal obstruction).
History of prior upper gastrointestinal surgery.
Significant abdominal injury that may affect gastric motility.
Need for immediate emergency surgical intervention before completion of study baseline assessments.
Trial population
Pediatric trauma patients aged 2 to 7 years presenting to the Emergency Department at Assiut University Hospital with hemorrhagic shock requiring hemodynamic resuscitation. Eligible participants are hemodynamically stable enough to undergo point-of-care gastric ultrasound (POCUS) examination without delaying critical emergency interventions. Patients with known preexisting gastrointestinal motility disorders, prior upper gastrointestinal surgery, significant abdominal injury affecting motility, gastric decompression before initial imaging, isolated head trauma, or immediate surgical needs are excluded.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
50 Participants
are grouped into 1 trial groupGroup A: Pediatric Trauma Resuscitation Cohort
Trial outcomes
Primary outcomes
1
Change in Gastric Residual Volume (GRV)
Change in gastric residual volume (mL/kg) from pre-resuscitation baseline to immediately after completion of hemodynamic resuscitation. Antral cross-sectional area (CSA) will be measured by point-of-care gastric ultrasound (POCUS) in the right lateral decubitus position (CSA = AP × CC × π/4), and gastric volume will then be estimated using the Spencer formula and normalized to body weight (mL/kg).
Time frame
Baseline, Up to 4 HoursLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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