Effect of Silicon Oil on Retinal Electrical Functions Using Multifocal Electroretinogram

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorMinia University

About this trial

Retinal detachment is one of the leading causes for permanent vision loss.Incidence of Rheugmatogenous Retinal Detachment (RRD) about 10.5 people per 100,000 population pars plana vitrectomy is the most popular and effective surgical options.

Tamponade agents as silicone oils are used to restore intraocular volume and apply surface tension to the detached retinal surface Silicone oil (SO) is a liquid containing polymerized siloxane with organic side chains. It has a high thermal stability, is hydrophobic, and chemically inert. The use of silicone oils as intraocular tamponades dates from 1962.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Patients with history of previous intraocular surgery.

Patients with combined traction-rhegmatogenous retinal detachment

Patients with ocular disease as glaucoma ,degenerative myopia,age related macular degeneration

Patients with poor fixation.

Trial design

Design model

Single group

Treatments tested in this trial

  • Multi focal electroretinogram

    Device

    to evaluat the effect of silicon oil on retinal function in the eyes that underwent Pars Plana Vitrectomy with Silicon oil tamponade for Rheugmatogenous Retinal Detachment. mfERG responses were recorded before and after Silicon oil removal .

Treatment groups

50 Participants
are divided into 1 treatment group
Group A: Effect of Silicon Oil on Retinal Functions after ViterectomyExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Retinal Functions after vitrectomy

Evaluation of the Function of the Eye Retina after Vitrectomy for all the participants

Time frame
1 Month to 3 Months
2

Electroretinogram Examination after vitrectomy

Electroretinogram examination which performed for all eyes after the vitrectomy as:When the light hits the eye, the photoreceptors (rods and cones) and other retinal cells generate small electrical impulses. The Electroretinogram captures and graphs these impulses to evaluate if these cells are functioning normally or not.

Time frame
1 Month to 3 Months

Secondary outcomes

Other outcomes

Sponsors and contacts

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