Effect of Sodium Chloride 5% Solution as an Adjuvant Treatment With Antimicrobial Therapy in the Treatment of Bacterial Infectious Keratitis

ConditionsInfectious Keratitis Adjuvant Treatment Bacterial Infectious Keratitis Sodium Chloride 5% Solution

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-60

SponsorSohag University

About this trial

This study aims to detect the effect of sodium chloride 5% solution as an adjuvant treatment with antimicrobial therapy in treatment of bacterial infectious keratits and to assess whether NaCl 5% accelerates epithelial healing, improves microbial eradication, and enhances visual outcomes in bacterial infectious keratitis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Clinically diagnosed bacterial infectious keratitis

Positive corneal scraping or strong clinical suspicion of bacterial cause.

Ability to provide informed consent and attend follow-up visits

Disqualifiers

• Fungal, viral, or acanthamoeba keratitis.

Recent (<7 days) topical corticosteroid use.

Corneal perforation or impending perforation.

History of hypersensitivity to study agents.

Trial design

Design model

Parallel

Treatments tested in this trial

Sodium chloride 5% solution
Drug
Use Sodium chloride 5% solution with usual anti microbial drugs
quinolones
Drug
Use of usual topical anti microbial treatment only

Treatment groups

40 Participants

are divided into 2 treatment groups

Group A: Intervention groupExperimental treatment 2 interventions

Group B: Control groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

Control of infection

Improvement of manifestation according to rate of healing

Time frame

6 months

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sohag University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: