In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine. The cough was graded based on the frequency and duration: Grade I, no cough; Grade II, a single mild cough; Grade III, multiple coughs with duration \<1 second; Grade IV, continuous coughing with a duration \>15 seconds.
Age between 18 and 65 years, 18 ≤ BMI (kg/m²) ≤ 30;
ASA grade I ~ III;
Scheduled elective surgery under general anesthesia with tracheal intubation.
Patients with chronic cough (cough lasting >8 weeks) or asthma;
Patients with a history of allergy to the drugs used during the study;
Patients with severe cardiovascular disease, intracranial lesions, eye lesions, or lung lesions.