Effect of Virtual Reality on Prostaglandin Levels in Adolescent Females With Primary Dysmenorrhea

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age17-21
SponsorBenha National University

About this trial

This study will be conducted to study the effect of virtual reality therapy on prostaglandin levels in adolescent females with primary dysmenorrhea.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 17- 21 years old.

The body mass index (BMI) < 30 kg/m2.

Unmarried females.

Females with dysmenorrhea pain.

Disqualifiers

Have a pathological disease related to reproduction.

Students who use analgesic drugs for 3 months/3 menstrual cycles.

Students with menstrual pain secondary to diagnosed organic or inflammatory causes.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Pharmacological treatment

    Drug

    All participants in the two groups will receive pharmacological treatment in the form of ibuprofen 400 mg, three times per day, during the first 2 days of menstruation, for 3 menstrual cycles.

  • Virtual reality

    Other intervention

    The experimental group will receive virtual reality during the first 2 days of menstruation, for 3 menstrual cycles.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: Pharmacological treatmentOther 1 intervention
Group B: Virtual reality + Pharmacological treatmentExperimental treatment 2 interventions

Trial outcomes

Primary outcomes

1

Visual Analogue Scale (VAS)

Participants in both groups will complete the visual analogue scale (VAS) before the start of treatment and after 3 menstrual cycles of treatment. The VAS is a 10 cm horizontal line on which the participants' pain intensity is represented by a point between the extremes of "no pain at all "and "worst pain imaginable". Each girl will be asked to mark a point on the line between the extreme that was related to her pain intensity. Then, the distance will be measured each time from the left end of the line to the marked point to obtain the VAS score for pain intensity of dysmenorrhea.

Time frame
12 weeks
2

Assessment of Prostaglandin Levels

Blood samples will be collected from each girl in both groups to measure the levels of plasma PGF2α before the start of treatment and after 3 menstrual cycles of treatment.

Time frame
12 weeks

Secondary outcomes

Other outcomes

Sponsors and contacts

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