Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-40
SponsorMinia University

About this trial

This study will be performed to assess the effect of inert prepared tooth paste loaded with Calcium Silicate Nanoparticles (CSNPs) and compare it to another one containing Sodium Fluoride Nanoparticles in the management of patients complaining of hypersensitivity and laboratory investigating the efficacy of CSNPs and NaFl Nps containing toothpaste in dentinal tubules occlusion.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Hypersensitive areas on facial surfaces of the teeth (incisors, cuspids, bicuspids, and first molars with exposed cervical dentine)

Areas with hard tissue erosion

cuneiform defect, pathological abrasion.

Gingival recession

Disqualifiers

chipped teeth

Defective restorations

fractured un displaced cuspids

deep dental caries

Trial design

Design model

Parallel

Treatments tested in this trial

  • toothpaste

    Other intervention

    group of patients with hypersensitive areas will use the calcium silicate toothpaste twice per day (morning and bedtime) the toothpaste will be applied uniformly using medium toothbrush to the hypersensitive surfaces for 30seconds. After that, the patient will rinse their mouth with plain water. the other group of patients will use the sodium fluoride toothpaste twice per day (morning and bedtime). The toothpaste will be applied uniformly using a medium toothbrush to the hypersensitive areas for 30 seconds after that the patients will rinse their mouth with plain water

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Toothpaste containing calcium silicate nanoparticlesActive comparator 1 intervention
Group B: Toothpaste containing sodium fluoride nanoparticlesActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

The Visual analogue scale

The Visual analogue scale on a scale (0 = no pain,10 = extreme pain).

Time frame
one year
2

The Verbal rating scale

The Verbal rating scale from to: (0 = no discomfort, 1=mild discomfort,2 = significant discomfort,3= significant discomfort lasting more than 10 seconds)

Time frame
one year

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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