Effects of Neuromuscular Electrical Stimulation With Neural Mobilization in Stroke Patients
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age45-65
SponsorRiphah International University
About this trial
The goal of this clinical trial is to learn if neuromuscular electrical stimulation combined with upper limb neural mobilization works to improve hand grip and upper limb function in post-stroke patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Diagnosed with ischemic stroke (duration ≥ 3 months post-stroke)
Patients with hemiparesis affecting the upper limb have a 15-30 score by the Fugl-Meyer Assessment.
Medically stable for physical therapy
Signed informed consent
Disqualifiers
Patients with pacemakers or implanted electrical devices
Upper limb fractures or contractures
Skin allergies or wounds over the stimulation site
Previously taking physiotherapy for the last 3 months.
Trial design
Design model
Parallel
Treatments tested in this trial
Conventional physical therapy
Other interventionNeural mobilization for median, radial, and ulnar nerves. 3 sets of 10 repetitions per nerve for 15 mins with 30 sec rest. Progressed based on tolerance and Range of Motion. Conventional rehabilitation consisted of standardized upper limb exercises, including ROM activities, strengthening exercises, stretching and tsk oriented training. Each treatment session was conducted for 45 minutes.
Neuromuscular Electrical Stimulation
Other interventionNeuromuscular Electrical Stimulation (NMES) applied to wrist extensors and finger flexors. Frequency: 35 Hz. Pulse width: 250 µs. Duty cycle: 10s on / 20s off. Intensity: Visible muscle contraction, within patient tolerance. Duration: 30 min Neuromuscular Electrical Stimulation (NMES) + 15 min rest/cool-down. Neural mobilization for median, radial, and ulnar nerves. 3 sets of 10 repetitions per nerve with 30 sec rest.
Treatment groups
44 Participants
are divided into 2 treatment groupsGroup A: Control groupActive comparator 1 intervention
Group B: Experimental groupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Handheld dynamometer
The standard Jamar hydraulic handgrip dynamometer with reliability (ICC = 0.95-0.98) was used according to established ASHT (American Society of Hand Therapists) protocols for the measurement of hand grip strength. The patient was seated with shoulder adducted, elbow flexed at 90°, forearm neutral, and wrist 0-30° extension. A total of three trials (kg) with a 1-minute rest between trials was done, and the mean of the 3 values was recorded.
Time frame
Baseline and 6th week2
Goniometer
A clinically accepted instrument with high reliability (ICC: 0.85 - 0.99), in accordance with standardised assessment protocols. Each movement was measured across three trails with a 1-minute rest period between trails, and the average of the three readings (in degrees) was used for statistical analysis.
Time frame
baseline and 6th week3
Fugl-Meyer Assessment - Upper Extremity
The scale assesses motor recovery by observing movement patterns that advance from proximal to distal joints and from mass synergistic actions to more selective, isolated movements following a stroke. It consists of 4 sections: shoulder-arm, wrist, hand, and coordination and speed. It comprises 33 test items, each scored on a three-point ordinal scale (0-2) with a maximum achievable score of 66. In stroke patients the scale has revealed high reliability (ICC: 0.993 - 0.997).
Time frame
Baseline and 6th weekLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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