Health TrialsbyHealthPanel

Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults

ConditionAging
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorUniversity of Regina

About this trial

The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).

A secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

if you are 50 years of age and older

if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.

Disqualifiers

if you have taken creatine supplements within 30 days prior to the start of the study

if you have pre-existing allergies to the placebo (corn-starch maltodextrin).

Trial design

Design model

Parallel

Treatments tested in this trial

  • Creatine Bolus 5

    Dietary supplement

    (Serving 1: 5 grams of creatine + 3 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1).

  • Creatine Bolus 3

    Dietary supplement

    (Serving 1: 3 grams of creatine + 5 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1).

  • Creatine Intermittent 5

    Dietary supplement

    (Serving 1: 2.5 grams of creatine + 5.5 grams of placebo in the morning, Serving 2: 2.5 grams of creatine + 5.5 grams of placebo at least 6 hours after Serving 1).

  • Placebo

    Dietary supplement

    (Serving: 8 grams of placebo in the morning; Servings 2: 8 grams of placebo at least 6 hours after Serving 1).

Treatment groups

52 Participants
are divided into 4 treatment groups
Group A: Creatine Bolus 5Experimental treatment 1 intervention
Group B: Creatine Bolus 3Experimental treatment 1 intervention
Group C: Creatine Intermittent 5Experimental treatment 1 intervention
Group D: PlaceboPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Whole-body lean mass (kg)

Bioelectrical impedance analysis

Time frame
baseline, week 16
2

Muscle Hypertrophy (cm)

B-mode ultrasound

Time frame
baseline, week 16
3

Strength (kg)

1-repetition maximum leg press and chest press

Time frame
baseline, week 16
4

Endurance (number of repetitions to fatigue)

Leg press and chest press

Time frame
baseline, week 16

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Regina

Lead sponsor

Iovate Health Sciences International Inc

Collaborator

Source ClinicalTrials.gov
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