Efficacy of Carbohydrate Loading in Diabetic Type 2 Patients Undergoing CABG Surgery on CPB
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorDamascus University
About this trial
Enhanced recovery after surgery protocols aim to optimize perioperative care and improve surgical outcomes. Preoperative carbohydrate loading has demonstrated benefits in reducing insulin resistance and improving patient outcomes. While non-diabetic patients benefit from this approach, its efficacy in diabetic type 2 patients undergoing CABG remains less understood. This study aims to address this gab by evaluating the physiological and clinical outcomes for carbohydrate loading in this specific population.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Missing data.
Patients outside the study period.
Patients undergoing other cardiac surgeries.
Patients diagnosed with type 1 diabetes mellitus.
Trial design
Design model
Parallel
Treatments tested in this trial
Carbohydrate loading before surgery
Dietary supplementCarbohydrate loading 2 hours before the surgery (400 ml of 12.5 maltodextrin and 400 ml of over-the-counter fruit-based lemonade)
Treatment groups
50 Participants
are divided into 2 treatment groupsGroup A: Intervention armActive comparator 1 intervention
Group B: Control armNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Short Insulin Tolerance Test (KITT)
Short Insulin Tolerance Test (KITT) will test changes in insulin tolerance postoperatively
Time frame
Preoperatively and up to 72 hours postoperativelySecondary outcomes
1
CRP levels
C-Reactive Protein levels in the blood
Time frame
Preoperatively and up to 72 hours postoperatively2
Arterial blood gases
Changes in arterial blood gases
Time frame
Preoperatively and up to 72 hours postoperatively3
Operative time
Total operative time, skin-to-skin
Time frame
Intraoperatively, skin-to-skin4
CPB duration
Total time spend using cardiopulmonary bypass perfusion
Time frame
Intraoperatively, using extracorporeal circulationSponsors and contacts
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Source ClinicalTrials.gov