About this trial
Cardiovascular disease is the leading cause of death among Veterans. Clinical trials are essential for developing better treatments, but Veterans remain underrepresented in these studies due to barriers including limited health literacy, lack of awareness, and mistrust. Current outreach approaches rely on either in-person physician conversations, which are limited by workforce constraints, or mailed letter invitations, which often fail to engage Veterans with limited health literacy. This study tests whether AI-generated video avatars can improve Veteran engagement in cardiovascular clinical trials.
Eligibility criteria
Qualifiers
Age 65 years or older
CHA2DS2-VASc Score of 3 or greater
Veteran receiving care within the VA Health Care System
Eligible to receive a mailed invitation through the parent VA Cooperative Studies cardiovascular trial recruitment process
Disqualifiers
Any exclusion criterion applied by the parent VA Cooperative Studies cardiovascular trial
Documented preference to opt out of VA research mailings
Age 18 years or older
Veteran receiving care at VAPAHCS
Trial design
Treatments tested in this trial
- AI-Generated Avatar Videos and Chatbot for Clinical Trial Outreach
Treatment groups
Locations
Sponsors and collaborators
Stanford University
Lead sponsor
Palo Alto Veterans Institute for Research
Collaborator
VA Palo Alto Health Care System
Collaborator