Endocan and Copeptin Serum Levels in Preterm Neonates With Respiratory Distress Syndrome
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age28-36
SponsorTanta University
About this trial
This work aims to investigate and compare the levels of serum endocan and serum copeptin on the first day of life and correlate their levels to the severity of respiratory distress in preterm neonates suffering from respiratory distress syndrome.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Prematurity.
Gestational age between 28 and 36 weeks.
Suffering from respiratory distress syndrome.
Disqualifiers
Intrauterine growth restriction (IUGR).
Hypoxic ischemic encephalopathy.
Multiple congenital anomalies.
Chromosomal abnormalities.
Trial population
This prospective study will be conducted at the Neonatal Intensive Care Unit (NICU), Pediatric Department, Tanta University Hospitals.
Trial design
Design model
Cohort
Time perspective
Retrospective
Treatments tested in this trial
Serum endocan
Diagnostic testSerum endocan will be measured by an enzyme-linked immunosorbent assay (ELISA) on the first day of life.
Serum copeptin
Diagnostic testSerum copeptin will be measured by an enzyme-linked immunosorbent assay (ELISA) on the first day of life.
Treatment groups
40 Participants
are divided into 2 treatment groupsGroup A: Group I2 interventions
Group B: Group II2 interventions
Trial outcomes
Primary outcomes
1
Serum endocan level for prediction of severity of respiratory distress syndrome
Serum endocan level for prediction of severity of respiratory distress syndrome (RDS) will be recorded.
Time frame
First day of lifeSecondary outcomes
1
Serum copeptin level for prediction of severity of respiratory distress syndrome
Serum copeptin level for the prediction of the severity of respiratory distress syndrome (RDS) will be recorded.
Time frame
5th day of life2
Serum endocan level for prediction of mortality
Serum endocan level for prediction of mortality will be recorded.
Time frame
First day of life3
Serum copeptin level for prediction of mortality
Serum copeptin level for prediction of mortality will be recorded.
Time frame
5th day of lifeSponsors and contacts
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Source ClinicalTrials.gov