About this trial
Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes clinical diagnosis difficult. It therefore seems important to improve the complementary examinations available to make the diagnosis more precise and to better study the effectiveness of the treatments implemented. The clinical examination and per-surgical findings of patients with deep pelvic endometriosis show a clear decrease in the mobility of the pelvic organs in relation to each other, but few studies have looked at this mobility, which could however have an implication in explaining the pathophysiology of the disease and the symptomatology of the patients, as well as in the detection of lesions preoperatively. The persistence of hypo-mobility could also help to understand treatment failures.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patient referred for suspected pelvic endometriosis requiring pelvic MRI
Female, nulliparous,
patient with signed written consent, patient with health insurance,
patient willing to comply with all study procedures and duration
Disqualifiers
BMI > 35,
history of hereditary collagen and elastic tissue disease,
history of pelviperitonitis,
history of major pelvic surgery,
Trial population
The population concerns patients referred to the Lille University Hospital for suspected pelvic endometriosis
Trial design
Cohort
Prospective
Treatments tested in this trial
Dynamic MRI Sequence
Other interventionAddition of a Dynamic MRI Sequence during the MRI examination performed in routine care
Treatment groups
Trial outcomes
Primary outcomes
the mean vertical displacement (in millimeters) measured on the anterior wall of the vagina between rest and maximum pushing force during dynamic MRI
Secondary outcomes
the mean vertical displacement (in millimetres) measured on the cervix between rest and maximum thrust effort during dynamic MRI.
the mean vertical displacement (in millimetres) measured on the posterior wall of the vagina between rest and maximum pushing force during dynamic MRI.
the measurement of variation in mean vertical displacement (in millimetres) on the wall of each pelvic organ at the push effort between the initial dynamic MRI of patients with
the statistical association between the symptoms of patients with endometriosis and the mean vertical displacement (in millimetres) on the wall of each pelvic organ at the push effort during dynamic MRI.
Initial symptoms are associated with initial dynamic MRI data and post therapeutic symptoms are associated with post-therapeutic dynamic MRI data. The symptoms of interest are dysmenorrhea, non-cyclic pelvic pain, dysuria, dychesia, transit disorders (diarrhea/constipation), and dyspareunia.
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