Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects

Trial statusAvailable
Trial phaseNot listed
Trial typeExpanded Access
Biological sexMale
Age20-35
SponsorKocaeli University

About this trial

The effect of physical activity on serum cartilage biomarkers is largely unknown. This study is critical to increase our knowledge of the physiological cartilage response to activities of daily living and dynamic tasks by focusing on healthy recreationally active individuals, thus improving our understanding of the complex relationship between cartilage health and the loading that occurs during different types of loading.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Healthy male volunteers between the ages of 20-35

Those who do physical activity for at least 30 minutes two to three days a week

17 healthy male individuals without any health problems will be included.

Disqualifiers

Those with acute or chronic injuries in their lower extremities

Those with musculoskeletal disorders in their lower extremities

Those who have undergone hip and/or knee surgery

Those with cardio-pulmonary problems that prevent them from exercising

Trial design

Treatments tested in this trial

  • Walking

    Other intervention

    Participants will perform 30 minutes of walking and cycling exercises. During the cycling and walking exercises, heart rate will be calculated using the Karvonen formula based on heart rate reserve. HRmax (maximum heart rate)=220-age HRR (%)(heart rate reserve)= (HR-HRrest)/(HRmax-HRrest)\*100 Blood samples will be collected from participants before starting the exercise, at the end of the 30-minute exercise session, and twice more at 30-minute intervals. The same participants will perform the cycling exercise half an hour later, and the same procedures will be applied.

  • Cycling

    Other intervention

    Cycling

Treatment groups

No treatment groups listed

Trial outcomes

This trial has no outcomes listed.

Sponsors and contacts

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Kocaeli University

Lead sponsor

Sakarya Applied Sciences University

Collaborator