Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorLaval University
About this trial
When mechanical ventilation is initiated, a humidification method should be chosen. There is two methods: heat and humidity exchanger filters or heated humidity. The second method is recognized to be more efficient, but many external factors can influence its performance. Insufficient humidity results in observable problems, such as difficult management of respiratory secretions.
The study compare two heated humidifiers already used in ICU.
Data will be collected retrospectively from June 1, 2021.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
≥ 18 years old
Admitted to intensive care
Under invasive mechanical ventilation with the usual indications for the use of a heated humidifier (prolonged invasive mechanical ventilation and / or protective ventilation requiring high respiratory rates.
Disqualifiers
Mechanical venitilation immediately after surgery (<24h)
Imminent extubation or planned intubation of very short duration (<24h)
Enrolled in the SAVE-ICU study in the group receiving volatile agents with the AnaConDa system.
Trial population
All patient in ICU on ventilation will be consider.
Trial design
Design model
Cohort
Time perspective
Retrospective
Treatments tested in this trial
MR850
DeviceThis humidifier will be used straight away for patients whose intubation is expected to last longer than 24 hours.
FP950
DeviceThis humidifier will be used straight away for patients whose intubation is expected to last longer than 24 hours.
Treatment groups
40 Participants
are divided into 2 treatment groupsGroup A: MR8501 intervention
Group B: FP9501 intervention
Trial outcomes
Primary outcomes
1
Endotracheal tube occlusion requiring emergency tube change
Under-humidification episodes are defined as follows: \- Occurence of endotracheal tube occlusion requiring emergency tube change
Time frame
At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)2
Bronchoscopy
Under-humidification episodes are defined as follows: \- Occurence of performing a bronchoscopy for a suspected sub-occlusion (thick or sticky secretions), and the total number of bronchoscopies performed per patient
Time frame
At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)3
Tracheal saline instillations
Under-humidification episodes are defined as follows: \- Occurence of tracheal saline instillations due to sticky secretions or suspected endotracheal tube sub-occlusion
Time frame
At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)4
Thick secretions
Under-humidification episodes are defined as follows: \- Occurence of tracheal secretions describe at thick secretions (rated at 5 on the secretions scale used at the hospital) or "sticky secretions" if specified
Time frame
At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)Secondary outcomes
1
Other elements that may be influenced by the quality of the humidification used during mechanical ventilation
These data will be collected: * mechanical ventilation time * length of stay in intensive care * ventilation pressures * use of bronchodilator aerosols. * Ambien room air temperature
Time frame
At the end of the mechanical ventilation period or at 21 days ( the first of the 2 occurred)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov