Evaluation of Long-term Isokinetic Training of Knee Joint
ConditionKnee Injuries and Disorders
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-60
SponsorPeking University Third Hospital
About this trial
The goal of this clinical trial is to assess the effectiveness of isokinetic rehabilitation training under optimal stiffness in patients undergoing knee joint rehabilitation. The main questions it aims to answer are:
* Does isokinetic training under optimal stiffness lead to greater force exertion compared to traditional bodyweight training? * What are the long-term (6-week) effects of isokinetic training under optimal stiffness on joint flexibility and muscle strength? Researchers will compare the effects of isokinetic training under optimal stiffness to traditional bodyweight training to see if isokinetic training produces superior improvements in muscle strength, flexibility, and overall functional recovery.
Participants will:
* Perform regular training sessions using a portable knee joint isokinetic trainer, customized to their optimal stiffness for maximum force exertion. * Engage in a 6-week rehabilitation program, with assessments at the beginning, and end of the study to evaluate changes in muscle strength, and functional recovery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age between 20-60 years.
Patients with unilateral anterior cruciate ligament (ACL) rupture (with or without meniscus injury), posterior cruciate ligament (PCL) rupture, meniscal tear (M), and patellar dislocation (PD).
Disqualifiers
Patients with major diseases or conditions such as coronary heart disease, myocardial infarction, heart failure, cerebral infarction, cerebral hemorrhage, or malignant tumors.
Pregnant or breastfeeding women and other special populations.
Patients who refuse to sign the informed consent form or are unable to complete the entire study process.
Patients currently infected with human immunodeficiency virus (HIV), or with a history of infectious hepatitis B or C.
Trial design
Design model
Parallel
Treatments tested in this trial
With robot assistance
DeviceUse a portable isokinetic device
traditional rehabilitation
BehavioralUse traditional isotonic and isometric rehabilitation
Treatment groups
12 Participants
are divided into 2 treatment groupsGroup A: Robot-assisted RehabilitationExperimental treatment 1 intervention
Group B: None-robot-assisted RehabilitationActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Cross-sectional area of the quadriceps
Using MRI，Up to 6 weeks
Time frame
Before 1st practice, and after 12th practice (6 weeks * 2 practices/week = 12 practices)2
Cross-sectional area of the hamstrings
using MRI， Up to 6 weeks
Time frame
Before 1st practice, and after 12th practice (6 weeks * 2 practices/week = 12 practices)3
Peak flexion and extension knee torque
Using an integrated torque sensor
Time frame
During each practice (6 weeks * 2 practices/week = 12 practices).4
Average flexion and extension knee torque
Time frame
During each practice (6 weeks * 2 practices/week = 12 practices).Secondary outcomes
1
Thigh circumference
10 cm proximal to the superior pole of the patella
Time frame
In each ptractice (6 weeks * 2 practices /week = 12 practices).2
Knee joint pain score (VAS score)
Up to 6 weeks，max. =100, min. =0, Visual Analogue Scale=VSA, A higher score indicates greater pain intensity.
Time frame
Before 1st practice, and after 12th practice (6 weeks * 2 practices/week = 12 practices)3
Surface electromyography signals of quadricep and hamstrings
SEMG signals are used to evaluate the instant effect brought by the optimal stiffness.
Time frame
During optimal stiffness measurementsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Peking University Third Hospital
Lead sponsor
Beihang University
Collaborator
Source ClinicalTrials.gov