Knee Injuries and Disorders

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Review clinical trials related to Knee Injuries and Disorders. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of Long-term Isokinetic Training of Knee Joint

The goal of this clinical trial is to assess the effectiveness of isokinetic rehabilitation training under optimal stiffness in patients undergoing knee joint rehabilitation. The main questions it aims to answer are: * Does isokinetic training under optimal stiffness lead to greater force exertion compared to traditional bodyweight training? * What are the long-term (6-week) effects of isokinetic training under optimal stiffness on joint flexibility and muscle strength? Researchers will compare the effects of isokinetic training under optimal stiffness to traditional bodyweight training to see if isokinetic training produces superior improvements in muscle strength, flexibility, and overall functional recovery. Participants will: * Perform regular training sessions using a portable knee joint isokinetic trainer, customized to their optimal stiffness for maximum force exertion. * Engage in a 6-week rehabilitation program, with assessments at the beginning, and end of the study to evaluate changes in muscle strength, and functional recovery.

Participants needed: 12
Trial details
Age: 20-60Biological sex: AllType: InterventionalSponsor: Peking University Third HospitalUpdated: Sep 15, 2026Locations: 1
Eligibility criteria

Age between 20-60 years. [+1]

Patients with major diseases or conditions such as coronary heart disease, myoca... [+4]

Status: Recruiting

Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health

Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability. Quantifying function in former athletes with and without a prior injury and non-athlete controls is critical to understanding long-term health trajectories in athletes and informing potential interventional studies. One modifiable factor that may be associated with long-term health in athletes is physical activity patterns. The purpose of this study is to evaluate strength, function, physical activity, dietary patterns, and cardiometabolic health among current and former competitive athletes and in nonathlete controls to evaluate the impact of prior knee injury and sedentary behavior as two potential determinants of later poor health and reduced function.

Participants needed: 450
Trial details
Age: 18-64Biological sex: AllType: ObservationalSponsor: Marquette UniversityUpdated: Feb 25, 2026Locations: 1
Eligibility criteria

Age 18-25 years OR age 40-64 years [+4]