Here's the revised version with the corrected treatment and follow-up session schedule:
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The aim of this clinical trial is to evaluate the effectiveness of bioactive toothpastes, desensitizing agents, and Er-YAG laser treatments in reducing dentin hypersensitivity. This study also aims to assess the safety and comparative efficiency of these treatment methods. The main research questions are:
* Do bioactive toothpastes, desensitizing agents, and laser treatments individually or in combination reduce dentin hypersensitivity? * Are there any adverse effects associated with these treatments?
Participants will:
* Be randomly assigned to one of four treatment groups, each using a specific toothpaste (Pro-Argin, Nano-Hydroxyapatite, NovaMin, or CPP-ACP), alongside desensitizing agents, laser treatments, or a placebo. * Receive two treatment sessions: the first at baseline and the second one week later. * Attend follow-up evaluations at the 2nd week, 1st month, and 3rd month to assess dentin hypersensitivity using the Visual Analog Scale (VAS) and dental unit air-water sprays.
Researchers will compare the outcomes across groups using statistical analyses (Kolmogorov-Smirnov, Kruskal-Wallis, and Pearson/Spearman tests) to determine the most effective approach for managing dentin hypersensitivity.
Individuals over the age of 18,
Individuals with good oral hygiene,
Individuals without systemic contraindications for treatment,
Individuals who are reliable for periodic follow-ups, cooperative, and willing to participate in the study,
Individuals with a history of alcohol, drug, or medication addiction,
Individuals known to be unable to attend follow-up sessions,
Individuals with allergies to any of the products used in the study,
Individuals with unstable mental or physical conditions,
Parallel
laser treatment
DeviceIn the laser treatment groups, the Fotona LightWalker® Erbium laser (2,940 nm) will be used, with each session lasting five minutes. During treatment, the energy density will be set to 20 J/cm², and the laser tip will be held perpendicular to the target area, applied in continuous and contact modes.
application of desensitizing agent
DeviceMix the product for 15 s. Apply in a thin layer on treatment area(s) with aid of a "microbrush", with no rinsing or removal
Placebo
Other interventionSimulation of a single layer application (15s) , with the aid of a "microbrush", on the surface of the tooth and with no rinsing or removal.
Change from Baseline in Dentin Hypersensitivity Scores Using VAS at 1 Week, 2 Weeks, 1 Month, and 3 Months After Treatment
Reduction in dentin hypersensitivity as assessed by the Visual Analog Scale (VAS) at baseline, immediately after treatment, 1 week, 2 weeks, 1 month, and 3 months post-treatment."
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Ege University
Lead sponsor
The Scientific and Technological Research Council of Turkey
Collaborator
This trial is not recruiting at the moment. You can still explore other options:
