About this trial
This comparative experimental study aims to evaluate the effectiveness of Sensory-Modulated Graded Weight-Bearing Physiotherapy (SMGWBP) in patients with knee osteoarthritis and compare treatment outcomes between male and female participants. Participants will receive a 6-week physiotherapy program with assessments conducted at baseline (pre-intervention), mid-intervention (3 weeks), and post-intervention (6 weeks) using validated outcome measures.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age between 40 and 60 years.
Diagnosed with Grade II or Grade III Knee Osteoarthritis according to Kellgren-Lawrence Classification.
Ability to ambulate independently without assistive devices.
Mild to moderate pain intensity with a Visual Analogue Scale score less than seven.
Disqualifiers
History of knee surgery within the previous six months.
Neurological disorders affecting balance, gait, or proprioception.
Severe cardiovascular disease limiting participation in exercise.
Rheumatoid arthritis or other inflammatory arthritic conditions.
Trial design
Parallel
Treatments tested in this trial
Sensory-Modulated Graded Weight-Bearing Physiotherapy
BehavioralA structured six-week Sensory-Modulated Graded Weight-Bearing Physiotherapy Programme consisting of three supervised sessions per week (18 sessions total). Each session includes warm-up, sensory modulation, proprioceptive training, graded weight-bearing strengthening, functional mobility exercises, and cool-down activities. The programme progresses through three phases: Weeks 1-2 focus on sensory activation and proprioceptive training; Weeks 3-4 on graded weight-bearing strengthening; and Weeks 5-6 on functional weight-bearing integration. Exercises are progressed according to participant tolerance, pain severity, and functional performance. Both male and female groups receive the same intervention.
Treatment groups
Trial outcomes
Primary outcomes
Change in Pain Intensity Measured by the Visual Analog Scale
To evaluate the change in pain intensity following a 6-week Sensory-Modulated Graded Weight Bearing Physiotherapy program in patients with knee osteoarthritis.
Change in Physical Function Measured by the Western Ontario and McMaster Universities Osteoarthritis Index
To assess changes in physical function following Sensory-Modulated Graded Weight-Bearing Physiotherapy.
Change in Proprioception Measured by the Joint Position Sense (JPS) Test
To assess changes in knee joint proprioception following Sensory Modulated Graded Weight-Bearing Physiotherapy
Change in Gait Performance Measured by the Six-Minute Walk Test (6MWT)
To assess changes in gait performance following Sensory Modulated Graded Weight-Bearing Physiotherapy
Secondary outcomes
Change in Health-Related Quality of Life Measured by the Short Form-36 (SF-36)
To assess changes in health-related quality of life following Sensory-Modulated Graded Weight-Bearing Physiotherapy
Treatment Compliance
To assess participants adherence to the prescribed 6-week Sensory Modulated Graded Weight Bearing Physiotherapy program. Treatment compliance determine based on the percentage of complete supervised treatment session
Sponsors and contacts
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