This study aims to enhance healing while minimizing invasiveness and restoring tissues to their proper structure and function by using patient specific sticky bone that will enhance the soft tissue reaction and maintain the graft volume stability and bone quality which stabilizes bone grafts, accelerates tissue healing, and reduces bone loss.
Patients of both genders requiring implants placement in anterior maxilla with horizontal bone defect.
Patients of age older than 20 years old.
Patients with adequate Inter-arch space.
Patients who were willing and fully capable to comply with the study protocol.
Heavy smokers (> than 10 cigarettes a day)
Patients with parafunctional habits
Patients with uncontrolled systemic diseases.
Patients with poor oral hygiene
Parallel
Mixture of Autogenous and Xenograft Particulates
Procedure/SurgeryThis group will receive guided bone regeneration using a 1:1 mixture of autogenous bone harvested from the mandibular ramus and xenograft bone substitute (e.g., Bio-Oss). The graft material will be covered with a titanium meshes. Standard flap design, fixation, and suturing techniques will be used
Patient-Specific Sticky Bone
Procedure/SurgeryThis group will receive guided bone regeneration using patient-specific sticky bone, created by mixing autogenous bone and xenograft with autologous fibrin glue (PRF). The sticky bone graft will be molded and applied directly to the defect site, covered with a titanium meshes, and stabilized using standard surgical protocol.
Radiographic and Histomorphometric Assessment for Guided Bone Regeneration using a Mixture of Autogenous and Xenograft Particulate Versus Patient-Specific Sticky Bone for Horizontal Anterior Maxillary Defect (Randomized Clinical Trial)
Radiographic and Histomorphometric Assessment for Guided Bone Regeneration using a Mixture of Autogenous and Xenograft Particulate Versus Patient-Specific Sticky Bone for Horizontal Anterior Maxillary Defect (Randomized Clinical Trial)
Radiographic outcomes will include CBCT-based measurements of horizontal ridge width and bone volume gain at the grafted sites. Histomorphometric evaluation will be performed using biopsies collected at re-entry to assess new bone formation, residual graft particles, and connective tissue. Comparisons will be made between autogenous/xenograft particulate grafts and patient-specific sticky bone in terms of bone regeneration effectiveness.
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