Harnessing Artificial Intelligence for Diagnosing Androgenetic Alopecia: A Training and Validation Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12-50
SponsorCairo University

About this trial

The aim of this study is to develop and validate deep learning models in diagnosis of male and female pattern hair loss, and assessment of its severity based on clinical and trichoscopic image by handheld dermoscopy and administrative data (age and sex).

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients with male or female pattern hair loss diagnosed clinically or suspected clinically and confirmed trichoscopically

Age of disease onset 12-50 years old

Both genders

Any grade of androgenetic alopecia

Disqualifiers

Patients with patchy hair loss or Telogen effluvium only.

Patients with cicatricial alopecia or diffuse alopecia areata

Patients with inflammatory scalp disorders (psoriasis, seborrheic dermatitis, lichen planopilaris and frontal fibrosing alopecia in a pattern distribution)

Lack of patient cooperation.

Trial population

Patients diagnosed clinically and trichoscopically with androgenetic alopecia of both genders and apparently healthy controls.

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

400 Participants
are grouped into 2 trial groups
Group A: androgenetic alopecia
Group B: normal controls

Trial outcomes

Primary outcomes

1

assessment of diagnostic capability of AI in AGA

Assess accuracy, sensitivity, specificity and positive predictive value of the trained AI models in differentiating AGA affected from non-AGA affected subjects using their macroscopic and trichoscopic images.

Time frame
1 year

Secondary outcomes

1

assessment of severity of androgenetic alopecia using AI

Assess accuracy, sensitivity, specificity and positive predictive value of the trained AI models in assessment of severity of androgenetic alopecia as regards: 1. Clinical classification (Sinclair scale for female pattern baldness and the Hamilton-Norwood scale for male pattern baldness) 2. Trichoscopic parameters: mean hair thickness (in micrometer, using planimetric analysis), hair density (frequency per cm2), proportion of terminal hairs, proportion of vellus hairs, number of hairs per follicular unit, presence of brown peripilar sign, yellow dots, and scalp honeycomb pigmentation.

Time frame
1 year
2

facilitation of AI assessment using macroscopic imagies

To compare the model's diagnostic accuracy using the macroscopic versus trichoscopic images alone

Time frame
1 year

Other outcomes

Sponsors and contacts

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