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High-Flow Nasal Oxygyen Therapy During Sedated Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration(EBUS-TBNA)

ConditionsHigh Flow Oxygen TherapyENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATIONSedationSedation ComplicationBlood Gas Analysis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorDr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

About this trial

This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Participants will be assigned to receive either high-flow nasal oxygen therapy or conventional oxygen therapy during the procedure. The incidence of respiratory complications, blood gas changes, and recovery outcomes will be compared between the two groups.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Age <18 years.

Pregnancy.

Requirement for endotracheal intubation or general anesthesia.

Severe hemodynamic instability.

Trial population

Adult patients (≥18 years) scheduled to undergo sedated endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) at Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital. Participants will be allocated to receive either high-flow nasal oxygen therapy or conventional oxygen therapy during the procedure

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • High-Flow Nasal Oxygen Therapy

    Device

    High-flow nasal oxygen therapy administered during sedated EBUS-TBNA procedures to provide enhanced oxygenation and respiratory support.

  • Conventional Oxygen Therapy

    Device

    Conventional oxygen therapy administered during sedated EBUS-TBNA procedures using standard oxygen delivery methods

Treatment groups

120 Participants
are divided into 2 treatment groups
Group A: Group H (High-Flow Nasal Oxygen Group)1 intervention
Group B: Group C (Conventional Oxygen Group)1 intervention

Trial outcomes

Primary outcomes

1

Respiratory Complications

Incidence of respiratory complications during sedated EBUS-TBNA, including hypoxemia, oxygen desaturation, apnea, airway obstruction, and the need for airway interventions.

Time frame
During the procedure

Secondary outcomes

1

Oxygen partial pressure (PaO2)

Changes in venous oxygen partial pressure(PaO2) measured at baseline and after sedated EBUS-TBNA

Time frame
Baseline and within 15 minutes after completion of the endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) procedure
2

Carbon dioxide partial pressure (PvCO2)

Changes in venous carbon dioxide partial pressure (PvCO2) measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA.

Time frame
Baseline and within 15 minutes after completion of the EBUS-TBNA
3

Venous pH

Changes in venous pH measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA

Time frame
Baseline and within 15 minutes after completion of the EBUS-TBNA procedure.
4

Venous Oxygen Saturation (SvO2)

Changes in venous oxygen saturation (SvO2) measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA.

Time frame
Baseline and within 15 minutes after completion of the EBUS-TBNA procedure.

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: