Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-40
SponsorInsel Gruppe AG, University Hospital Bern

About this trial

The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas. Researchers want to determine how deeply ABC affects ovarian tissue and to generate data on the safety of this surgical technique.

Participants will undergo standard laparoscopic surgery for ovarian endometriomas. During the planned surgical procedure, Argon Beam Coagulation will be applied to the ovarian surface according to the study protocol. The treated tissue will subsequently be excised as part of the planned surgery and analyzed histologically to measure the depth of tissue penetration.

Eligibility criteria

Qualifiers

Female patients aged 18-40 years.

Indication for surgical treatment of ovarian endometrioma based on clinical symptoms and/or imaging findings.

Diagnosis of ovarian endometrioma ≥3 cm confirmed by preoperative imaging (ultrasound and/or MRI).

Planned laparoscopic cystectomy.

Disqualifiers

Expected lack of compliance or inability to understand the study procedures.

Previous surgical procedures on the affected ovary.

Recurrent ovarian endometrioma.

Pregnancy or breastfeeding.

Trial design

Treatments tested in this trial

  • Argon Plasma Coagulation

Treatment groups

50 Participants
are divided into 1 treatment group