About this trial
Periodontal diseases are a prevalent issue, often leading to gingival recession, where the gingival margin recedes, exposing the tooth root and causing various problems. Gingival recession can be managed through both non-surgical and surgical interventions The non-surgical approach often involves plaque control and addressing any underlying inflammatory conditions. However, in cases of advanced recession, surgical treatment may be necessary Several treatment techniques have been proposed, which can be divided into pedicle and free grafts. The latter can also be classified as free gingival grafts (FGG) or as connective tissue grafts (CTG). Other treatment options include soft tissue substitutes or regenerative therapies Harvesting graft from the palate has several problems, such as pain, inflammation, bleeding, flap necrosis, and infection at the donor site. For this reason, we need a substitute for soft tissue graft harvesting Carbopol polymers, also known as carbomers, are widely utilized in pharmaceutical formulations for their excellent mucoadhesive properties. This high molecular weight, cross-linked acrylic acid polymers are particularly effective in enhancing the adhesion of formulations to mucosal surfaces, thereby improving drug delivery and bioavailability
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients of both genders with ages more than 18 years.
At least two adjacent teeth in maxillary or mandibular anterior sextant with Cairo classification (RT1 or RT 2) labial GR defect.
Good general health with no contraindications for periodontal surgery (American Society of Anesthesiologists I).
Non-smoker patients.
Disqualifiers
Pregnant and lactating women.
Teeth exhibiting pathologic mobility.
Mal alignment teeth.
Patients under active orthodontic therapy.
Trial design
Parallel
Treatments tested in this trial
Ascorbic acid
DrugAscorbic acid induce gingival healing
Treatment groups
Trial outcomes
Primary outcomes
Gingival recession height
The distance from the cementoenamel junction to the gingival margin
Locations
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: