Human Neural Correlates of Multi-Timescale Inference

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Colorado, Boulder

About this trial

Adult epilepsy patients who are undergoing intracranial monitoring will participate in a simple behavioral task during the clinical recording period.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Epilepsy patients undergoing intracranial electrode monitoring for uncontrolled seizures.

no lesions identified in the participants' brains

capable of giving consent

Disqualifiers

seizure activity during task recording

electrodes in regions of interest are identified to be the seizure focus

task performance outside of the normal range as determined from online studies with healthy participants

Trial population

Epilepsy patients with intractable seizures who are undergoing clinical continuous intracranial recordings of the brain's electrical activity to assess the seizure focus location.

Trial design

Design model

Case-only

Time perspective

Other

Treatments tested in this trial

  • Decision-making task

    Behavioral

    Patients will be asked to play a decision-making game in which they hear a tone and must identify its source.

  • eye tracking

    Behavioral

    Patients will have simultaneous eye-tracking performed while playing the decision-making game

Treatment groups

30 Participants
are divided into 1 treatment group
Group A: Flexible Decision Making Task2 interventions

Trial outcomes

Primary outcomes

1

Pupil size changes with respect to task features

pupil size will be measured with a portable eye-tracking device and correlated with task features

Time frame
continuous recording during task, up to 30 minutes
2

Behavioral Responses

Patient selects one of two choices on each trial using the computer keyboard

Time frame
Approximately 10 seconds per trial, up to 30 minutes total
3

Intracranial electrode recordings to measure changes in brain activity during decision making

Intracranial neural recordings from patients who are implanted with electrodes for clinical purposes tha take place during the decision-making task

Time frame
duration of the task, approximately 30 minutes

Secondary outcomes

Other outcomes

Sponsors and contacts

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University of Colorado, Boulder

Lead sponsor

University of Colorado, Denver

Sponsor institution

This trial is not recruiting at the moment. You can still explore other options: