Hyaluronic Acid and I-PRF Mixture for TMJ Disc Displacement Management
ConditionTMJ Disc Displacement With Reduction
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorMansoura University
About this trial
The aim of this study is to evaluate the efficacy of hyaluronic acid and I-PRF mixture for intra-articular injection following arthrocentesis in the management of TMJ reducible disc displacement.
Eligibility criteria
Qualifiers
Age: 18 - 45 years.
Patients with disc displacement with reduction in any of the TMJs.
arthralgia.
Limited unassisted mouth opening.
Disqualifiers
Patients with previous history of TMJ minimally invasive interventions.
Patients with autoimmune or connective tissue diseases affecting the joints.
Patients with neurological disorders.
Patients with a history of condylar fractures or ankylosis.
Trial design
Treatments tested in this trial
- 18 joints that receive arthrocentesis using 100 ml of ringer lactate solution
- Arthrocentesis followed by hyaluronic acid injection
- Arthrocentesis followed by injection of hyaluronic acid and betamethasone mixture
- Arthrocentesis followed by injection of hyaluronic acid and I-PRF mixture
Treatment groups
72 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov