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Imaging of Electrical Properties by MRI: Investigation of Age-Related Changes

ConditionHealthy Subjects
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6+
SponsorCentral Hospital, Nancy, France

About this trial

The goal of this study is to build a database of personalized EP (Electrical Properties) maps (accounting for age, anatomical location, and tissue complexity), obtained via MRI, to improve electromagnetic safety assessments, especially in the context of MRI. The EP values derived from this study are expected to be more accurate than current literature values, leading to more realistic specific absorption rate (SAR) modeling and improved patient safety. To investigate age-related differences, the study will include three distinct age groups.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Person aged between 6 and 12, 20 and 40 years or aged 70 years and above

Person affiliated with a social security scheme or beneficiary of such a scheme

Person, or parent/legal guardian in the case of minors, who has received full information about the organization of the study and has signed the informed consent form

Disqualifiers

Contraindication to undergoing an MRI examination or the presence of an MRI-incompatible medical device

Person presenting a pathology or tissue damage in the examined areas that may affect the measured MRI parameters

Pregnant woman, woman in labor, or breastfeeding mother

Person deprived of liberty by judicial or administrative decision, or persons undergoing psychiatric care

Trial design

Design model

Parallel

Treatments tested in this trial

  • Magnetic Resonance Imaging (MRI) examination

    Device

    MRI examination of the head and neck, and torso for the measurement of electrical properties

Treatment groups

120 Participants
are divided into 3 treatment groups
Group A: Children between 6 and 12 years oldExperimental treatment 1 intervention
Group B: Adults between 20 and 40 years oldExperimental treatment 1 intervention
Group C: Adults aged 70 and aboveExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Conductivity in S/m at the head level in subjects aged 6 to 12 years

Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 6 to 12 years

Time frame
Baseline (J0)
2

Conductivity in S/m at the head level in subjects aged 20 to 40 years

Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 20 to 40 years

Time frame
Baseline (J0)
3

Conductivity in S/m at the head level in subjects aged 70 and above

Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 70 and above

Time frame
Baseline (J0)
4

Conductivity in S/m at the neck level in subjects aged 6 to 12 years

Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 6 to 12 years

Time frame
Baseline (J0)

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Central Hospital, Nancy, France

Lead sponsor

Source ClinicalTrials.gov
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