About this trial
The main objectives of our proposed study are to determine the effects of mango consumption on immune and cognitive functions in free-living college going young adults aged 18-30 years
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Male and female college students aged 18-30 years
Disqualifiers
known intolerance or allergy to mangos
regular intake of mangos and/or fruits of a similar nutritional content such as peach, nectarine, papaya, apricot and cantaloupe
using cognition and/or immune-boosting supplements or vitamins
recent exposure to antibiotics and corticoids
Trial design
Parallel
Treatments tested in this trial
Mango group
Dietary supplementParticipants will consume 1.5 cups of mangos per day for 12 weeks.
Treatment groups
Trial outcomes
Primary outcomes
Changes in lymphocyte populations
Immunophenotyping will be performed by flow cytometry to measure the number of T helper, T cytotoxic, Naive and memory cells and B cells
Changes in Lymphocyte activity
The production of lymphocytes will be measured in the supernatant using enzyme linked immunosorbent assay (ELISA)
Changes in cytokine production
The cytokines produced due to lymphocyte activity will be measured in the supernatant using enzyme linked immunosorbent assay (ELISA)
Changes in serum inflammatory cytokine concentration
changes in the concentrations of the inflammatory cytokines will be performed on serum using enzyme linked immunoassay (ELISA) will include hs-CRP, interleukin (IL)-1B, IL-6, TNF a, IL-10, IL-2, IFN-γ, E-selectin,
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Loma Linda University
Lead sponsor
National Mango Board
Collaborator
This trial is not recruiting at the moment. You can still explore other options: