Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorKidSIM Simulation Program

About this trial

Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses. The Coronavirus Disease 2019 (COVID-19) pandemic was caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients infected with SARS-CoV-2 experience unusually high rates of critical illness that needs advanced airway management and intensive care unit admission. Bag-valve-mask (BVM) ventilation, endotracheal Intubation (ETI) and chest compressions are sometimes required for critically ill COVID-19 patients, and may contribute to a high risk of infection amongst Health Care Workers (HCW). To lessen HCW risk during high-risk procedures, a device called an aerosol box has been developed to place over the head of the patient, shielding the provider's face from virus droplets suspended in the air.

The purpose of this research study is to better understand how particles disperse during AGMPs, more specifically during the provision of cardiopulmonary resuscitation (CPR). The project team hopes what is learned from the project can help inform infection control measures. This could help make changes to the clinical environment and make it safer for HCW's. The investigators intend to explore how an aerosol box performs in reducing contamination of HCW's who perform critical airway interventions during resuscitation events.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Attending physician, fellow or resident in adult or pediatric emergency medicine, pediatric intensive care, general pediatrics or pediatric/adult anesthesia

Adult or Pediatric Advanced Life Support certification.

Attending physician, resident, fellow, nurse, respiratory therapist, physician assistant or health care aide

Basic Life Support, Adult or Pediatric Advanced Life Support certification

Disqualifiers

Decline to provide informed consent

Unable to perform tasks required of the role due to physical limitations.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Aerosol box

    Device

    The aerosol box is a transparent, plastic cube covering the patient's head and shoulders, with circular access ports on the front of the box allowing for access to manage the airway. An additional four access holes (i.e. two on either side of the box) allow for airway assistants to access the patient airway.

Treatment groups

240 Participants
are divided into 2 treatment groups
Group A: Aerosol BoxExperimental treatment 1 intervention
Group B: No Aerosol BoxNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Percentage of overall excellent CPR

A continuous measure defined as percentage of chest compressions (CC) meeting American Heart Association guidelines for CC depth and rate at the same time during resuscitation

Time frame
Immediately after simulated resuscitation

Secondary outcomes

1

Time to successful intubation

The time required by the team to successfully pass the endotracheal tube after patient becomes apneic.

Time frame
Immediately after simulated resuscitation
2

CC fraction

The percentage of time performing CC during cardiac arrest.

Time frame
immediately after simulated resuscitation
3

Time to initiation of CPR

The time required for the team to initiate CPR after the patient becomes pulseless

Time frame
Immediately after simulated resuscitation
4

Disease particle concentration (ppm) at head of bed and over patient torso

Measurement of the concentration of simulated disease particles in the air at certain positions at defined time points.

Time frame
Measured at 2, 4, 6, 8, and 10 minutes of simulated resuscitation.

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

KidSIM Simulation Program

Lead sponsor

University of Calgary

Sponsor institution

Canadian Institutes of Health Research (CIHR)

Collaborator