The goal of this observational study is to learn whether hypoalbuminemia in post surgical patients receiving cefoperazone/sulbactam therapy poses them to the risk of developing coagulopathy. It will also study that what are the other risk factors for the development of cefoperazone/sulbactam induced coagulopathy. The main questions it aims to answer are : • Does hypoalbuminemia increase the risk of cefoperazone/sulbactam coagulopathy in post operative surgical patients?
* What is the incidence of cefoperazone/sulbactam induced coagulopathy in normoalbuminemic vs hypoalbuminemic patients. * Does renal function, nutritional status, dose and duration of therapy affect coagulopathy development? * What are the independent risk factors for the development of cefoperazone/sulbactam induced coagulopathy? Patients' coagulation tests will be followed during the duration of cefoperazone/sulbactam therapy to identify coagulation development.
Patients >= 18 years
Post-operative surgical patients
Receiving cefoperazone/sulbactam therapy for at least 72 hours.
Willing to give informed consent
Chronic liver disease
History of any inherited coagulation disorder
On anticoagulant therapy
Any massive blood loss requiring blood transfusion