Impact of Visceral Adiposity on Postoperative Atrial Fibrillation After CABG

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorKartal Kosuyolu Yuksek Ihtisas Education and Research Hospital

About this trial

Obesity has become a major public health problem in both developed and developing countries, with a continuous increase particularly since the 1980s. Moreover, it is a well-established metabolic risk factor for diabetes mellitus, hypertension, and various types of cancer, as well as cardiovascular diseases such as heart failure and coronary artery disease. Body mass index (BMI) is calculated by dividing body weight in kilograms by the square of height in meters and is widely used as an indicator of obesity. However, BMI does not quantitatively reflect body fat distribution and fails to account for components such as skeletal muscle and bone mass. Therefore, interest in assessing body fat distribution has increased, and in recent years, studies evaluating the correlation between anthropometric, biochemical, and anatomical measurements and clinical outcomes have become more frequent. In particular, it is acknowledged that abdominal obesity cannot be accurately represented by BMI alone and is primarily associated with visceral adipose tissue (VAT). The aim of this study is to evaluate the association between preoperative visceral and subcutaneous adipose tissue measurements (VAT and SAT), assessed by ultrasonography in patients scheduled for open-heart surgery, and the development of postoperative atrial fibrillation.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Elective isolated coronary artery bypass graft surgery (on-pump)

Age ≥18 years, planned prospectively in 300 patients

Disqualifiers

Patients requiring urgent or emergency surgery

Off-pump coronary artery bypass graft surgery

Surgeries other than isolated coronary artery bypass graft

Patients in whom abdominal ultrasound measurement cannot be performed (e.g., due to severe deformity, wounds, edema)

Trial population

Adult patients (≥18 years) scheduled for coronary artery bypass graft surgery.

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

  • Postoperative AF Group

    Other intervention

    In patients undergoing coronary artery bypass graft surgery, ultrasound-guided measurements of visceral and subcutaneous adipose tissue will be performed preoperatively. The relationship between adipose tissue thickness and the development of postoperative atrial fibrillation will be evaluated by comparing patients who develop AF with those who do not.

  • Non-AF Group

    Other intervention

    In patients undergoing coronary artery bypass graft surgery, ultrasound-guided measurements of visceral and subcutaneous adipose tissue will be performed preoperatively. The relationship between adipose tissue thickness and the development of postoperative atrial fibrillation will be evaluated by comparing patients who develop AF with those who do not.

Treatment groups

300 Participants
are divided into 2 treatment groups
Group A: Group 1: Postoperative AF Group1 intervention
Group B: Group 2: Non-AF Group1 intervention

Trial outcomes

Primary outcomes

1

Effect of visceral adipose tissue thickness on postoperative atrial fibrillation

Preoperative ultrasound-guided measurement of visceral adipose tissue thickness will be performed. The association between visceral fat thickness and the development of postoperative atrial fibrillation will be evaluated.

Time frame
Within 7 days after coronary artery bypass graft surgery or until hospital discharge

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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