Influence of Cataract Surgery on Corneal Biomechanical Properties in Patients With Pseudoexfoliation Syndrome
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-85
SponsorKata Culina
About this trial
Pseudoexfoliation syndrome is associated with alterations in the biomechanical properties of the cornea. This prospective observational cohort study aims to evaluate changes in corneal biomechanical properties after standard phacoemulsification cataract surgery in patients with pseudoexfoliation syndrome compared with patients without pseudoexfoliation syndrome. Corneal hysteresis (CH) and corneal resistance factor (CRF) will be measured using the Ocular Response Analyzer before surgery and at postoperative day 1, day 7, and day 30. The study will enroll patients undergoing routine cataract surgery to compare postoperative changes in CH and CRF between the pseudoexfoliation and control groups.
Eligibility criteria
Qualifiers
adults aged 50 years and older
presence of age-related cataract requiring phacoemulsification cataract surgery
presence of pseudoexfoliation syndrome (PEX group) or absence of pseudoexfoliation syndrome (control group)
ability and willingness to provide written consent
Disqualifiers
previous ocular surgery,
corneal disease,
glaucoma or ocular hypertension,
dry eye disease (Schirmer test <10 mm, tear break-up time <5 seconds or positive fluorescein staining),
Trial design
Treatments tested in this trial
- Not listed
Trial groups
70 Participants
are grouped into 2 trial groupsSponsors and collaborators
Kata Culina
Lead sponsor
Eye Clinic Medic Zuljan Jukic
Sponsor institution
Source ClinicalTrials.gov