Internal Jugular Vein Collapsibility Index for Volume Status Assessment in Preeclampsia in Correlation With Normotensive Parturients : a Prospective Observational Cohort Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-40
SponsorTanta University

About this trial

This study aims to assess and analyze volume status in preeclamptic patients and compare these parameters with those of normotensive pregnant ones based on the change in internal jugular vein ultrasound-based indices.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Singleton parturients from 18 to 40 years old.

Normotensive group: uncomplicated normotensive pregnancy with systolic blood pressure below 140 mmHg and diastolic blood pressure below 90mmHg without proteinuria.

Proteinuria (≥300 mg in a 24-hour urine sample)

Alb/Cr ratio ≥30 mg/mmol,

Disqualifiers

Parturients with pre-existing cardiac & vascular disease affecting blood volume and vascular compliance: (Valvular or congenital heart disease, arrhythmia, previous history of venous thromboembolism, chronic kidney disease, gestational diabetes).

multiple gestations

known thyroid disorders or chronic hypertension

patients with BMI >40 and patients requiring emergency delivery.

Trial population

Patients admitted at obstetric theater in Tanta University Hospital

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

80 Participants
are grouped into 2 trial groups
Group A: Preeclamptic Group
Group B: Control Group

Trial outcomes

Primary outcomes

1

Measuring internal jugular vein (IJV) collapsibility index

Measuring internal jugular vein (IJV) collapsibility index at end expiratory phase just before the induction of anesthesia and its correlation with normotensive parturients to determine the cut off value of fluid status in preeclamptic patient

Time frame
Intra-operative

Secondary outcomes

1

Association between internal jugular vein ultrasound-based indices and severity of Preeclampsia.

Time frame
Intra-operative
2

Value of internal Jugular vein collapsibility index in predicting post spinal hypotension

Time frame
Intra-operative

Other outcomes

Sponsors and contacts

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