Intraoperative Paravertebral Block and Postoperative Complications

ConditionsVideo-assisted Thoracoscopic Surgery (VATS)Lung Cancer (Diagnosis)Pulmonary Infections Respiratory Failure Without Hypercapnia Pleural Effusion Due to Another Disorder (Disorder)Atelectasis Bronchospasm Pneumothorax Pulmonary Embolism (Diagnosis)Bronchopleural Fistula Acute Respiratory Distress Syndrome (ARDS)

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-80

SponsorTongji Hospital

About this trial

This study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Male or female participants aged 18 years or older.

Scheduled to undergo thoracic surgery via Video-Assisted Thoracoscopic Surgery (VATS) or Robotic-Assisted Thoracoscopic Surgery (RATS), including wedge resection, segmentectomy, lobectomy, or mediastinal surgery.

Signed informed consent obtained prior to study participation. -

Disqualifiers

Patients who refuse to provide informed consent.

Anesthesiologists who have not received training in ultrasound-guided paravertebral block (PVB-US).

History of ipsilateral thoracic surgery.

Conversion to open thoracotomy during the procedure.

Trial design

Design model

Parallel

Treatments tested in this trial

Paravertebral Block (PVB)
Procedure/Surgery
Participants in this arm will receive a paravertebral nerve block (PVB) performed intraoperatively under ultrasound guidance prior to the thoracic surgical procedure. The block will target the relevant thoracic vertebral levels corresponding to the surgical site. Standard local anesthetic agents will be administered according to institutional protocols. This intervention aims to provide perioperative analgesia, reduce postoperative pain, and potentially decrease the incidence of postoperative complications. All participants will also receive standard intraoperative monitoring and anesthesia management as per routine clinical practice.

Treatment groups

500 Participants

are divided into 2 treatment groups

Group A: Paravertebral Block (PVB)GroupExperimental treatment 1 intervention

Group B: Control GroupNo intervention 0 interventions

Trial outcomes

Primary outcomes

Postoperative Complications

Postoperative complications following thoracic surgery will be assessed as the primary outcome. These complications include pulmonary infection, respiratory failure, pleural effusion, atelectasis, bronchospasm, pneumothorax, aspiration-induced lung injury, pulmonary embolism, bronchopleural fistula, and acute respiratory distress syndrome (ARDS). The incidence of these complications will be systematically recorded and analyzed to evaluate the clinical impact of the intervention.

Time frame

1 to 3 months postoperatively

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Tongji Hospital

Lead sponsor

Source ClinicalTrials.gov

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