This study will compare intravenous magnesium sulfate with intravenous lidocaine for reducing the cardiovascular response to endotracheal intubation in adult patients undergoing general anesthesia. Eligible participants will receive either magnesium sulfate or lidocaine before endotracheal intubation. Heart rate and blood pressure will be recorded at predefined time points before and after intubation to compare the effectiveness of the two interventions in attenuating the hemodynamic response to laryngoscopy and endotracheal intubation.
age 18-70 yrs
male and female patients
patients undergoing elective or emergency procedures under general anesthesia
pregnancy
anticipated difficult airway
Parallel
Magnesium Sulphate infusion
Drugintravenous magnesium Sulphate 30mg /kg diluted in 100ml normal saline, administered 90 sec before induction of general anesthesia
heart rate 5minutes after endotracheal intubation
systolic blood pressure 5 minutes after endo tracheal intubation
mean arterial pressure 5 minutes after endotracheal intubation
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