Investigation of Autonomic Stress Response Patterns in College Students With Varying Physical Activity Levels
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-30
SponsorBeijing Sport University
About this trial
This study aims to investigate the differences in cardiovascular stress response patterns among individuals with various physical activity levels (sedentary controls and different types of athletes). By synchronously monitoring ECG, heart rate, skin sympathetic nerve activity (SKNA), blood pressure, and cardiac output, the study will characterize physiological dynamics during resting, orthostatic challenge, cold pressor stress, and maximal exercise.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
The study population consists of 60-80 healthy adult volunteers (college students). Participants are categorized into five distinct groups based on their habitual physical activity levels and training backgrounds: 1) Sedentary controls, 2) Endurance athletes, 3) Strength athletes, 4) Technical athletes, and 5) Traditional ethnic sports practitioners (e.g., Tai Chi). Gender balance is maintained across all groups.
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Cardiopulmonary Exercise Testing
Diagnostic testCardiopulmonary Exercise Testing (CPET) is a non-invasive, integrated assessment of the cardiovascular, respiratory, and muscular systems' responses to physical stress.
Treatment groups
60 Participants
are divided into 4 treatment groupsGroup A: Sedentary Control1 intervention
Group B: Endurance Athletes1 intervention
Group C: Strength Athletes1 intervention
Group D: Traditional Ethnic Sports1 intervention
Trial outcomes
Primary outcomes
1
Heart Rate Variability
Time-domain metrics (e.g., RMSSD, SDNN) derived from ECG recordings to evaluate cardiovagal modulation and cardiac autonomic balance.
Time frame
Baseline (10-minute rest), during the 10-minute mental stress test, and during the cardiopulmonary exercise test (approx. 20 minutes)2
Skin Sympathetic Nerve Activity
Integrated average SKNA (aSKNA) and burst metrics measured via surface electrodes to assess sympathetic nerve firing
Time frame
Baseline (10-minute rest), during the 10-minute mental stress test, and during the cardiopulmonary exercise test (approx. 20 minutes)Locations
Sponsors and contacts
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Source ClinicalTrials.gov
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