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IVC Collapsibility Index or CVP as a Predictor of Fluid Responsiveness in Pediatric Sepsis

ConditionsSepsisSeptic ShockPerforated ViscusHospitalism in Children
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-5
SponsorTanta University

About this trial

Pediatric population who suffered from sepsis due to perforated viscus will receive fluid resuscitation guided by either central venous pressure or guided by IVC collapsibility index.

The method of guidance of fluid therapy will be applied pre, intra, and postoperatively.

Primary outcome will be the length of hospital stays, while the secondary outcomes will be the incidence of complications and the length of PICU stays

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Pediatric patients aged 1 to 5 years presented with septic shock due to perforated viscus according to definition of the American College of Critical Care Medicine and International Pediatric Sepsis Consensus.

Disqualifiers

Refusal of the parents to participate in the study

Obesity

Congenital heart diseases

Severe arrythmias

Trial design

Design model

Parallel

Treatments tested in this trial

  • Central venous catheter

    Procedure/Surgery

    Central venous catheter will be introduced to measure central venous pressure

  • IVC collapsibility index

    Diagnostic test

    In supine position, IVC will be assessed in the anteroposterior plane in the subxiphoid view using two-dimensional mode till an optimal view of IVC entering the right atrium will be obtained. Then, measurement of its collapsibility will be done.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: Group I (CVP)Experimental treatment 1 intervention
Group B: Group II (IVC)Experimental treatment 2 interventions

Trial outcomes

Primary outcomes

1

the length of hospital stays

The number of days from admission of the child till discharge

Time frame
within first 28 days

Secondary outcomes

1

The length of PICU stays

The number of days from admission of child to ICU till discharge from ICU.

Time frame
within first 28 days
2

The incidence of complications

The incidence of acute kidney injury, ARDs, acidosis, severe oedema, or mortality.

Time frame
within first 28 days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Tanta University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: