Health TrialsbyHealthPanel

Laser vs Lontophoresis in KOA

ConditionKnee Arthritis Osteoarthritis
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age45-65
SponsorKafrelsheikh University

About this trial

This randomized controlled trial aims to compare the effectiveness of laser therapy and iontophoresis in patients with knee osteoarthritis. The study will evaluate pain reduction, functional improvement, and knee joint mobility following

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

* Age 45-65 years.

Diagnosed primary knee osteoarthritis (Grade I-II).

Both genders.

Ability to follow treatment protocol.

Disqualifiers

* Previous knee surgery.

Intra-articular injections within last 6 months.

Pacemaker.

Skin lesions at treatment area.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Low-Level Laser Therapy

    Device

    Low-level laser therapy combined with conventional physical therapy for patients with knee osteoarthritis to reduce pain and improve functional mobility and knee joint range of motion

  • Iontophoresis

    Device

    Iontophoresis using dexamethasone combined with conventional physical therapy for patients with knee osteoarthritis to reduce pain and improve physical function and knee joint mobility

  • Conventional Physical Therapy Only

    Other intervention

    Conventional physical therapy program for patients with knee osteoarthritis including therapeutic exercises, stretching, strengthening exercises, and pain relief modalities to improve knee function and mobility.

Treatment groups

66 Participants
are divided into 3 treatment groups
Group A: Group A:Active comparator 2 interventions
Group B: Group BActive comparator 2 interventions
Group C: Group CActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Pain intensity measured using Visual Analogue Scale (VAS)

Time frame
Baseline and after 4 weeks of treatment
2

Functional disability measured using WOMAC.

Time frame
Baseline and after 4 weeks of treatment
3

3. Knee Range of Motion (ROM).

Time frame
Baseline and after 4 weeks of treatment

Secondary outcomes

1

Change in physical function assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function Subscale

The WOMAC Physical Function Subscale consists of 17 items assessing difficulty in performing daily activities. Scores range from 0 to 68, with higher scores indicating worse physical function.

Time frame
Baseline (Day 0) and Week 4
2

2. Reduction of joint stiffness.

Time frame
Baseline and after 4 weeks of treatment
3

Change in daily activities performance assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Physical Function Subscale

The WOMAC Physical Function Subscale consists of 17 items assessing difficulty in activities of daily living. Scores range from 0 to 68, with higher scores indicating worse functional limitation.

Time frame
Baseline (Day 0) and Week 4

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Kafrelsheikh University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: